A modern take on the cases of Sherlock Holmes, with the detective now living in New York City.
Jonny Lee Miller / Lucy Liu / Aidan Quinn / Jon Michael Hill
Watson is implicated in a DEA investigation into doctors writing illegal prescriptions, so she and Holmes look for the culprit using her medical license to sell drugs.
When Shinwell is framed for a gang killing, Holmes and Watson have three days to catch the real killer before Shinwell is sent back to jail.
Henny Penny the Sky is Falling (HD, New, TV-14) When the city commends the work of Captain Gregson's unit, Gregson pushes for Holmes and Watson to be included; a financial analyst is murdered.
Holmes learns a secret about Captain Gregson's girlfriend when she hires him for a case she wants kept off of Gregson's radar. Also, Holmes and Watson join the NYPD's search for an abducted woman.
Watson seeks help from a former patient to find a serial bomber.
When Morland offers to use his influence to have Sherlock and Joan reinstated as consultants to the NYPD, Sherlock's mistrust of his father makes him question his motivation to help. Also, ...
Sherlock faces the consequences of his relapse, and his father arrives to try to fix the situation. Joan and Sherlock, trying to get back on NYPD's good side, search for a missing woman working the theory she was killed by her husband.
Holmes and Watson take on an investigation of a personal nature when Holmes' recovery sponsor Alfedo suddenly disappears.
Holmes and Watson are drawn into an Internet war when a member of an anonymous hacker group is murdered.
A driver for a ride sharing company is intentionally run over by a city cab, Sherlock and Joan wonder if it's a case of professional jealousy. A romance Sherlock has with a longtime Irregular complicates when she makes a shocking request.
A murder victim turns out to have been instantly frozen at the time of death; Watson is forced to have an awkward conversation with her brother after learning he is having an affair.
Holmes investigates himself when he becomes a suspect in a murder that took place during the height of his addiction; clues make Holmes question his innocence.
Holmes and Watson follow a blood trail into the world of wrongful death compensation when they investigate a series of murders in which the killer leaves envelopes of cash on the victims. ...
Sherlock and Detective Bell investigate the kidnapping of two zebras from the zoo.
Holmes and Watson are faced with a very large suspect pool when a debt collector is murdered; Andrew wants Watson to meet his father.
As Kitty begins to unravel due to the imminent threat to her safety, Sherlock and Joan intensify their efforts to help her. Also, the origin of Sherlock and Kitty's relationship is revealed. Stuart Townsend guest stars.
Watson starts her new job as an investigator for an insurance firm, but ends up joining forces on a case with Sherlock when a threat to Kitty emerges.
While Kitty tries to find a runaway teen, Sherlock and Joan work a case in which the murder of a brilliant bioengineer looks to be at the hands of a drug cartel. Also, Joan makes a major ...
When a nurse Watson used to work with asks for her help finding their missing acquaintance, the woman's trail leads Watson and Holmes to another person who has disappeared. Also, Sherlock ...
Holmes and Watson join forces with the NYPD after a police officer is murdered. Also, Sherlock searches for the creator of a "recovery blog" who is posting personal statements he has made in sobriety meetings.
A bored Sherlock forces his investigative services onto Joan, who is trying to locate a woman who has been missing for five years, and the only clue is the smell of nutmeg at the site of ...
Holmes and Watson search for a thief who committed murder to steal a rare map. Meanwhile, Watson becomes concerned with Sherlock's escalating interference into Kitty's burgeoning personal life. Mamie Gummer guest stars.
A man's hand is found in the streets. Sherlock and his new protégé investigate to find the rest of the body. Meanwhile Sherlock finds Watson's book written about him.
An A.I. computer is suspected for the murder of its creator; Sherlock and the team go to work to solve the case.
Sherlock helps a math genius from his network of "Irregulars" experts after he stumbles upon a body while participating in a math puzzle competition. Meanwhile, Joan attempts to extend an ...
When Holmes and Watson join forces on a double homicide, Sherlock's new apprentice, Kitty, threatens the investigation when she allows her jealousy of Sherlock and Joan's work rapport to override her better judgment.
Holmes returns to New York with a new apprentice and a renewed interest in working with the NYPD after being fired by London's MI6. Unfortunately, Joan, the NYPD's new go-to PI, must give her approval first.
Rising tension between Sherlock and Watson bring their partnership to a crossroads, but they endeavor to put their differences aside while they help Sherlock's brother, Mycroft, who faces ...
Mycroft's handler at MI6 asks Sherlock to investigate the death of a mentally disturbed operative. Watson tries to cope with her feelings about the kidnapping, as well as Mycroft's deceptions.
With Watson kidnapped, the Holmes brothers are extorted to buy her back by acquiring something the gangsters greatly value. As the clock runs down on Watson's life, Sherlock is forced to work with his despised brother Mycroft.
When Sherlock's brother Mycroft makes a surprise return to New York, his motivations cause discord between Sherlock and Joan. Meanwhile, a missing person case takes Sherlock and Joan inside the world of unmanned aeronautics.
Holmes and Watson must find the source of anthrax that may be used for a terrorist attack.
A serial killer known for biting his victims appears to be killing again, even though he was presumed dead.
When a famous cancer researcher is found dead, Holmes and Watson must determine if the scientist's untimely demise was tied to his latest cutting-edge invention. Meanwhile, Bell is finally cleared to re-enter the field.
Holmes and Watson consult on a case in which a man suspected of murdering his wife years ago receives a ransom demand for her safe return. Meanwhile, Lestrade overstays his welcome at the brownstone and seems unwilling to leave.
Tensions rise when Holmes and Watson are forced to partner with Gareth Lestrade, Sherlock's former Scotland Yard colleague, on a bombing investigation. Sean Pertwee guest stars as Gareth Lestrade.
Holmes' latest investigation takes him inside a professional dance company when an up-and-coming ballerina is murdered. Meanwhile, Watson embarks on a solo enquiry to find a homeless veteran when his friend alleges he was abducted.
When Joan revisits one of Sherlock's cold cases, she discovers an unsolved murder is connected to a rare prehistoric fossil. Meanwhile, Sherlock finds himself in uncharted territory when ...
When a body is found in a barrel, Holmes and Watson launch an investigation into the mafia's ties to the murder. Meanwhile, Sherlock attempts to make amends with Detective Bell. Peter Gerety and Paul Sorvino guest star.
Holmes and Watson come face to face with Moriarty when their one-time adversary is brought in as a consultant on a kidnapping case. Meanwhile, Detective Bell continues his struggle on the ...
When a hedge fund manager who was also running a Ponzi scheme is murdered, Holmes and Watson must determine which of his clients is guilty. Also, Sherlock contemplates sponsoring a fellow recovering addict.
When an investigation goes horribly wrong, Sherlock must testify in an official police inquiry which jeopardizes his and Watson's future with the NYPD.
Holmes and Watson uncover the identity of a serial killer whose case has gone cold and find themselves butting heads with the NYPD.
When a beautiful young woman is murdered, Holmes and Watson investigate her ties to a billionaire CEO. Meanwhile, Mycroft makes a case for Sherlock to move back to London.
Sherlock's brother, Mycroft, arrives in New York and enlists Holmes and Watson to help solve a case involving his former fiancee. Meanwhile, Sherlock has a difficult time accepting Mycroft and Joan's relationship. Rhys Ifans guest stars.
Captain Gregson's team learns a bit about his personal life after his home is invaded. Holmes and Watson track the gunman.
Holmes and Watson find themselves digging through the dark world of the mob to find a killer when they discover the body of a former assassin.
A dominatrix finds her client dead in S&M gear. When poison is revealed to be the cause of death, the nanny becomes a suspect.
When Holmes and Watson set out to track down a civil contractor who leaked classified information, their lives are disrupted when they are targeted by the group of cyber-activists protecting him. Tony Award Winner Steve Kazee guest stars.
When a well-respected mathematician is found dead, Holmes and Watson set out to solve a murder and the purpose of the highly guarded equation he was trying to decipher. Jeremy Jordan Guest ...
Holmes and Watson travel to London to help track down an old mentor and investigate an unsolved mystery. Rhys Ifans guest stars.
Holmes reconnects with Irene, his one true love that he thought had been taken from him by Moriarity. He tries to protect her as she recovers from her trauma but he soon learns that it isn't she that needs protection.
Moriarty asks Holmes to find out who murdered a mechanic in Brooklyn. Despite Watson's protests, Holmes thinks this case will help him uncover Moriarty's true identity, but it will, in fact, lead Holmes to something much worse.
A man connected to the classification of a valuable building as a landmark trust dies when his pacemaker is deliberately short circuited. Holmes soon learns the one behind the murder is an old nemesis known to him only as "Moriarty".
A blackmailer uses tapes of underage girls to get money from their fathers. When Holmes witnesses the blackmailer's murder, it becomes a race to find out who his accomplice is and prevent the videos from being released on the Internet.
In the middle of a winter storm, Holmes and Watson must solve the murder of a guard during a botched robbery and unravel the killer's true plan. The pair also get an interesting new roommate.
Watson works a case on her own about a woman who has disappeared while Holmes deals with a subway murder. As they work their separate cases they gradually appear to be connected, even though they can't determine exactly how.
A wealthy scientist comes to Holmes with a unique case: he believes he has been "poisoned" with a genetic disorder. Holmes has to determine how a healthy person can be contaminated with a genetic disease that no one in his family has.
Detective Bell is nearly killed while driving home one night. A just-released felon is the first suspect but, when he's killed, suspicion moves to Bell's brother who, unlike the dedicated ...
Holmes' former drug supplier comes to him for help to find his kidnapped daughter. He agrees to help him despite Watson's protests. When Holmes appears stymied, the former dealer encourages Holmes to go back on drugs, hoping it will help him solve the cas
A convicted killer who is supposed to donate a kidney to his sister ends up killing the surgical staff before escaping. Holmes is forced to work with a profiler (whom he can't stand) because she supposedly can predict what he will do next.
Holmes discovers a man running an internet conspiracy site is dead. As he follows the chain of clues, he becomes aware of the "Red Team" and the trail leads him further down the rabbit hole than he ever imagined.
Sherlock is called in on a case and immediately recognizes the work of an old foe from Britain. Sherlock sees it as a chance at redemption in catching the man, but first he needs to control his own emotions about the murderer.
The manager of a high-end hotel that caters to diplomatic VIPs is found dead in the hotel's laundry. After first suspecting a connection to a prostitution ring, Holmes believes the answer lies in her treacherous past.
Micah Erlich hires Holmes to solve urgently the robbery of diamonds in David Batonvert's Manhattan exchange from his world-reputed security firm's top-range vault model, the 'impregnable' ...
Oriental studies professor Trent Annunzio was killed with a bullet in each eye. Sherlock works out he was a Mahjong gambling addict and in which establishment, where he forces the owner to ...
While Watson struggles with Holmes over finding a new sponsor, they work a case of a bombing of an Internet company. The bomb was planted four years ago but it's inconceivable that anyone would plan a bombing so far into the future.
Sherlock identifies new murders as the modus operandi of Wade Crewes, the serial killer whose arrest made Captain Thomas Gregson's NYPD career. Their friendship is strained by necessary ...
After a small jet crashes killing four people, Holmes battles both the police and the NTSB when he believes one of them was murdered before the crash occurred. Meanwhile, Watson confronts Holmes over a past friend, someone named Irene.
During a visit to a hospital's morgue to do some experiments, Holmes deduces that a terminally ill patient has been murdered. Is this an isolated incident or is there an "Angel of Mercy" operating in the hospital?
Holmes is hired by a Wall Street firm to find a missing executive. He finds the man, murdered, and then detects a pattern of mysterious deaths throughout the company's branches. But who could be benefiting from all of the murders?
Holmes is excited to be consulted about the latest strike of 'balloon man', a serial killer who focuses on children. Analyzing the crime scene, Holmes' deductions lead to the recovery of ...
Two heirs of a fortune are murder suspects, but one sister has an undeniable alibi and the other is a coma patient. Holmes is baffled as to how a coma patient could be the killer until another addict in his support group gives him an idea.
Sherlock Holmes, fresh out of rehab, is teamed with a sobriety partner, a former surgeon named Watson. They have to learn to work together even as they tackle their first case, the mysterious death of a doctor's wife.